MASH 2022 Spring Symposium
Friday, March 18th: Virtual kick-off
Saturday, March 19th: in-person event at Granite Links Golf Course in Quincy, MA
VIRTUAL KICK-OFF EVENT:
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Clif Chapman
4pm - 5pm March 18th Microsoft Teams |
"Troubleshooting Histology: H&E and Special Stains"
Get ready for a fast-paced workshop filled with information on how to recognize sub-optimal histology slides, troubleshoot the cause and develop a solution to the issue. The first half will focus on the hematoxylin and eosin (H&E) stain: how to obtain a consistently optimal stain, how to recognize when something goes amiss and how to remedy the situation. The second half will zoom in on selected special stains which have reputations for yielding inconsistent results. Participants should be able to take this knowledge back to their own laboratories to assist them in their everyday histology work. |
SYMPOSIUM AGENDA:
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7am - 8am
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Registration and Vendor Hall
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8am - 9am
Nancy Ruiz |
"CINtec PLUS: A dual immunostaining for p16/Ki-67 to detect cervical lesions: Triaging equivocal cervical cytology and HPV screening"
Cervical cancer is a highly preventable disease with vaccination, proper screening and treatment. However, ~14,480 new cases of invasive cervical cancer will be diagnosed and approximately 4,290 women will die from cervical cancer per year, with HPV causing >99% of these cases. Pap testing has played a key role in reducing cervical cancer since its introduction in the 1940s, however, it isn’t without its limitations. Pap normal and HPV- positive screening (discrepant co-testing) can either lead to unnecessary referral of women for colposcopy or cause a 12 months delay in follow up, allowing the exacerbation of actively transforming HPV infections. Co-expression of p16 and Ki-67 is a strong indicator that an HPV infection is undergoing oncogenic transformation. CINtec Plus Cytology, a new FDA-approved test for triage of discrepant co-testing results, provides greater sensitivity than Pap alone by finding disease earlier in the screening process. |
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9am - 10am
Sara Eglitis |
"Companion Diagnostics: In Vitro Diagnostics for Targeted Therapeutics"
In vitro diagnostics is a category of regulated medical devices which are used to collect, prepare, or examine human tissue for clinical use such as diagnosis of disease or determining state of health. Companion diagnostic devices are in vitro diagnostics developed to support the therapeutic drug, biologic, or device selection for a specific patient. In the era of precision medicine, there is a greater awareness of the need to identify key targets to treat conditions. In the United States, the Food and Drug Administration (FDA) maintains an approved list of companion diagnostic devices which is regularly updated. Current pathways include premarket approval (PMA), premarket notification 510(k) clearance, humanitarian device exemption (HDE), de novo classification request, and investigational device exemption (IDE). This presentation will describe the pathways recently used for an immunohistochemistry (IHC) test associated with an intravenous therapeutic and a reverse-transcriptase quantitative polymerase chain reaction (RQ-PCR) test associated with an oral capsule. |
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10am - 10:30am
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Coffee break
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10:30am - 11:30am
Kim Packard Cynthia Chzranowski |
"Discovery: Beyond Human - The Pet Perspective"
Do you enjoy Science, the final frontier? Discovery is exploration. It is the action, process, insight, invention, realization or unearthing of. Discovery’s core purpose is to enhance health and protect lives through the identification of evidence, awareness of risk factors and management of health. The microscopic observation of both human and animal reveals that tissue cells share morphological features and are arranged in an ‘orderly’ pattern that achieves the tissue’s function. A video interview with a veterinarian will be included to show how closely we work together as a team to provide the best possible patient care. Come, join the journey of exploration into veterinary pathology! |
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11:30am - 12:30pm
Nicholle Cyr |
"The Role of the Histologist in a Mohs Surgical Laboratory"
Mohs surgery was a technique developed to microscopically control surgery for the treatment of common skin types. A fast or rapid Mohs, most commonly performed in a surgical office, requires knowledge and skill by the histologist to provide an accurate assessment of the margins of the specimen. The histologist has many responsibilities within the Mohs surgical laboratory, including technical precision, troubleshooting techniques, and creating a positive, trusting relationship with the surgeon. |
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12:45pm - 1:45pm
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Buffet lunch and raffle prizes
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